Table 1. Main Baseline characteristics according to dialysis modality.
| PDa patients | HDb patients | p | |
|---|---|---|---|
| (n = 237) | (n = 237) | ||
| Males (%) | 137 (58) | 146 (61.8) | 0.45 |
| Age (years) | 52 [42;63] | 55 [43;63] | 0.11 |
| Smoker (former/current) (%) | 135 (57) | 137 (58) | 0.92 |
| Diabetes (%) | 43 (18.1) | 43 (18.1) | 1 |
| Hypertension (%) | 219 (92.4) | 199 (84) | 0.007 |
| Dyslipidemia (%) | 153 (64.6) | 123 (47.7) | <0.001 |
| Etiology of renal disease (%): | 0.670 | ||
| Diabetic nephropathy | 25 (10.5) | 27 (11.4) | |
| Vascular disease | 23 (9.7) | 29 (12.2) | |
| Others | 189 (79.7) | 181 (76.4) | |
| Dialysis time (months) | 13.7 [6.2;28.9] | 14.3 [6.41;28.6] | 0.91 |
| Body mass index (kg/m2) | 26.4 [23.3;29.2] | 25.3 [23;28.6] | 0.23 |
| Systolic Blood Pressure (mmHg) | 140 [129;159] | 135 [120;151] | 0.001 |
| Diastolic Blood Pressure (mm Hg) | 83 [77;94] | 80 [70;88] | <0.001 |
| Pulse Pressure (mmHg) | 56 [45;69] | 55 [46;63] | 0.53 |
| Serum glucose (mmol/L) | 5.05 [2.96;6.10] | 5.05 [4.56;6.10] | 0.838 |
| Urea (mmol/L) | 21.5 [17.6;25.8] | 20.8 [15.8;25] | 0.07 |
| Creatinine (μmol/L) | 682.5 [519.8;884] | 727.5 [574.6;884] | 0.1 |
| Total colesterol (mmol/L) | 4.58 [3.99;5.20] | 3.91 [3.37;4.53] | <0.001 |
| HDL-cholesterol (mmol/L) | 1.22 [1.01;1.48] | 1.09 [0.90;1.29] | <0.001 |
| LDL-cholesterol (mmol/L) | 2.66 [2.07;5.15] | 2.07 [1.63;2.64] | <0.001 |
| Triglycerides (mmol/L) | 1.34 [1.07;1.87] | 1.41 [1.03;1.92] | 0.75 |
| Serum uric acid (μmol/L) | 345.1 [303.4;401.6] | 362.9 [321.3;425.4] | 0.006 |
| hs C-Reactive Protein (nmol/L) | 19 [8.95;49.9] | 22.47 [10.09;58.66] | 0.23 |
| Albumin (mol/L) | 0.59 [0.54;0.62] | 0.59 [0.54;0.64] | 0.025 |
| Hemoglobin (mmol/L) | 7.2 [7.01;8.01] | 7.26 [6.70;7.76] | <0.001 |
| Corrected calcium (mmol/L) | 2.3 [2.20;2.42] | 2.26 [2.16;2.36] | <0.001 |
| Phosphate (mmol/L) | 1.6 [1.35;1.84] | 1.54 [1.25;1.79] | 0.035 |
| iPTH (pmolL) | 22.7 [14.9;35.4] | 25.7 [14.3;36.4] | 0.23 |
| 25-hydroxy-vitamin D (nmol/L) | 28.9 [20.9;41.2] | 37.4 [26.4;48.7] | <0.001 |
| 1-25-hydroxy-vitamin D (pmol/L) | 13.6 [9.72;19.9] | 13.8 [9.31;22.3] | 0.54 |
| Treatments | |||
| Antihypertensive (%): | 214 (90.3) | 159 (67.1) | <0.001 |
| ACEIc (%) | 66 (27.8) | 41 (17.3) | 0.008 |
| ARBsd (%) | 111 (46.8) | 54 (22.8) | <0.001 |
| Diuretics (%) | 128 (54) | 45 (19) | <0.001 |
| Statins (%) | 137 (57.8) | 110 (46.4) | 0.017 |
| Phosphate binders (%): | 198 (83.5) | 189 (79.7) | 0.343 |
| Binders without Cae (%) | 126 (53.2) | 138(58.2) | 0.309 |
| Binders with Cae (%) | 42 (47.2) | 40 (47.1) | 1 |
| Cae intake (binders) (gr/day) | 1.5 [1;2] | 1.65 [1;3] | 0.027 |
| Calcitriol/Paricalcitol (%) | 97 (40.9) | 122 (51.5) | 0.027 |
| Calcifedol /%) | |||
| Cholecalciferol (%) | 27 (11.4) | 8 (3.38) | 0.002 |
| Cinacalcet (%) | 11(4.64) | 8 (3.38) | 0.640 |
| Antiplatelet drugs (%): | 27 (24.1) | 68 (28.7) | 0.297 |
| ESAf(%) | 181(76.4) | 198 (83.5) | 0.066 |
| Renal transplantation centre (%) | 88 (37.1) | 62 (26.2) | 0.014 |
| Plaque presence (%) | 123 (51.9) | 143 (60.3) | 0.08 |
| Number of territories with plaque | 2 [1.0;3.0] | 2 [1.0;3.0] | 0.285 |
| cIMTg (mm) | 0.65 [0.56;0.79] | 0.70 [0.6;0.84] | 0.009 |
| Ankle-Brachial index (%) | |||
| ABI < 0.9 | 37 (15.7) | 23 (9.91) | 0.08 |
| ABI >0.9-<1.4 | 175 (74.5) | 144 (62.1) | 0.005 |
| ABI > 1.4 | 23 (9.79) | 65 (28) | <0.001 |
Data are presented as median [interquartile range], mean (standard deviation) or n(%).
a Peritoneal dialysis
b Hemodialysis
c Angiotensin converting enzyme inhibitors
d Angiotensin II receptor blockers
e Calcium
f Erythropoiesis stmulating agents
g Common carotid artery intima media thickness