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. 2018 Apr 20;6(2):28. doi: 10.3390/diseases6020028

Figure 3.

Figure 3

Implication of SODs in the neuroprotection against Alzheimer’s disease via the signaling of PI3K/AKT/PTEN/GSK-3β pathway, and examples of molecules known to act on the regulatory pathways are shown. PI3K/AKT/PTEN/GSK-3β pathway and SODs may contribute to neuroprotection in AD. Hammerheads mean inhibition. Note that some critical events have been omitted for clarity