Table 1.

Technical factors concerning percutaneous biopsy of bone metastases.

Imaging Guidance	Fluoroscopy (incl. Cone beam CT)	Ultrasound (incl. Fusion imaging)	Computed Tomography (incl. CT fluoroscopy)	Magnetic Resonance Imaging
Biopsy Techniques	Co-axial technique	Tandem technique	Fine needle aspiration biopsy	Core needle biopsy
Diagnostic Accuracy	70–96% depending upon target’s size and location, benign or malignant character, number of samples, on-site presence of cytopathologist
Complications	Procedure related mortality rate <0.05%—quality improvement threshold for overall incidence of complication of 2%
References	Veltri et al. CVIR 2017: CIRSE guidelines on percutaneous needle biopsy [6]		Gupta et al. JVIR 2010: Quality improvement guidelines for percutaneous needle biopsy [5]