Table 3.
Antifungal target proteins related to lipid metabolism.
| Gene | Annotation | Fungi Tested * | Reference |
|---|---|---|---|
| AFUA_4G13680 | Phosphatidylserine synthase | C. albicans | [33] |
| AFUA_2G15970 | Phosphatidylethanolamine N-methyltransferase | S. cersvisiae et al. | [55] |
| AFUA_1G09050 | Methylene-fatty-acyl-phospholipid synthase | A. nidulans | [35] |
| AFUA_3G04210 | Fatty acid synthase α subunit FasA | C. neoformans | [41] |
| AFUA_3G04220 | Fatty acid synthase β subunit FasB |
C. neoformans
C. parapsilosis |
[41,56] |
| AFUA_5G01960 | Phosphate transporter Pho88 |
A. nidulans
A. fumigatus |
[51] |
| AFUA_3G12320 | Lipase/Serine esterase | S. cerevisiae | [57] |
| AFUA_2G09040 | Vacuolar transporter chaperone (Vtc4) |
Ustilago maydis
Candida |
[53,54] |
* “Fungi tested” means that fungi listed here are already well described in literature and the researchers have published evidence supporting them as promising drug targets.