Skip to main content
. 2018 Jun 18;11(6):e007451. doi: 10.1161/CIRCIMAGING.117.007451

Figure 3.

Figure 3.

Changes in left ventricular mass (LVM), diffuse fibrosis, and replacement fibrosis in aortic stenosis before and after valve replacement. Longitudinal changes in LVM index (LVMi), diffuse fibrosis (indexed extracellular volume [iECV]), and replacement fibrosis (late gadolinium enhancement [LGE]) before and after valve replacement (AVR) are illustrated with 2 example patients (A and B). All 3 measures increase exponentially as stenosis severity increases (patient A, natural history cohort), and new areas of LGE are seen on follow-up imaging (red arrows). However, after AVR, cellular hypertrophy regresses more quickly than diffuse fibrosis, and replacement fibrosis seems unchanged (patient B, white arrows). AVR indicates aortic valve replacement; and Vmax, peak aortic-jet velocity.