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Receiver operating characteristic curves related to pretherapeutic metabolic 18F-FCH PET parameters (TLA and MBTV) and platelet toxicity at the end of 223Ra treatment. Acc, accuracy; AUC, area under the curve; 18F-FCH, fluorine-18-fluorocholine; MBTV, metabolically active bone tumor volume; Se, sensitivity; Sp, specificity; TLA, total bone lesion activity; VPN, negative predictive value; VPP, positive predictive value.
