Table 2.
Biochemical parameters of hypertensive patients with and without metabolic syndrome
| Patients with MetS (n = 157) | Patients without MetS (n = 79) | p-value | |
|---|---|---|---|
| Cholesterol (mg.dL-1) | 166 (139 – 192) | 179 (150 – 200) | 0.06 |
| LDL-c (mg.dL-1) | 88 (70 – 111) | 98 (73 – 118) | 0.19 |
| HDL-c (mg.dL-1) | 43 (37 – 49) | 57 (51 – 65) | < 0.01 |
| Triglycerides (mg.dL-1) | 142 (97 – 199) | 81 (68 – 115) | < 0.01 |
| FBG (mg.dL-1) | 107 (95 – 130) | 91 (86 – 97) | < 0.01 |
| HbA1c (%) | 6.30 (6– 7.40) | 5.90 (5.50 – 6) | < 0.01 |
| hs-CRP (mg.dL-1) | 0.39 (0.17 – 0.65) | 0.25 (0.11 – 0.48) | 0.02 |
| Na (mEq.dL-1) | 141 (140 – 143) | 142 (138 – 143) | 0.61 |
| K (mEq.dL-1) | 4.40 (4.10 – 4.70) | 4.30 (4.20 – 4.60) | 0.82 |
| PAC (ng.dL-1) | 83 (48 – 162) | 65 (41 – 125) | 0.10 |
| CC (ml.min-1.(1,73m2)-1) | 80 (55 – 97) | 71 (53 – 94) | 0.53 |
| Creatinine (mg.dL-1) | 0.93 (0.80 – 1.12) | 0.95 (0.77 – 1.20) | 0.97 |
| Renin (pg.ml-1) | 23 (12 – 64) | 30 (11 – 80) | 0.78 |
| Urea (mg.mL-1) | 35 (26 – 44) | 36 (28 – 44) | 0.81 |
| Cortisol (ug.dL-1) | 14 (10 – 20) | 14 (10 – 16) | 0.44 |
| Leptin (ng.mL-1) | 21.0 (14.40–41.60) | 15.70 (6.30–33.20) | < 0.01 |
| Adiponectin (µg.dL-1) | 5.30 (2.60– 7.80) | 7.50 (3.80 – 11.90) | < 0.01 |
| LAR | 4.81 (2.14 – 10.80) | 2.22 (1.10 – 5.20) | < 0.01 |
| LAR > 3.72, n (%) | 85 (54) | 24 (30) | < 0.01 |
Values are expressed as mean ± standard deviation or median (1st, 3rd quartiles), according to data distribution. Continuous variables were compared using unpaired Student´s t-test or Mann-Whitney test, according to data distribution. Categorical variables were compared by chi-square test. MetS: metabolic syndrome; LDL-c: low density lipoprotein-c; HDL-c: high density lipoprotein-c; FBG: fasting blood glucose; HbA1C: glycated hemoglobin; hs-CRP: high-sensitivity c-reactive protein; Na: serum sodium; K: serum potassium; PAC: plasma aldosterone concentration; CC: creatinine clearance; LAR > 3.7: leptin adiponectin ratio > 3.7 (the cutoff value was determined by median value).