| Overall symptoms |
|
|
|
| A change in behavior such as irritability or crying |
12 (34.3%) |
19 (52.8%) |
31 (43.7%) |
| |
|
|
|
| Gastrointestinal symptoms |
|
|
|
| Frequent regurgitation or vomiting related to cow’s milk protein |
23 (65.7%) |
29 (80.6%) |
52 (72.3%) |
| Persistent distress or colic (>3 h/day ≥3 days/week over a 3-week period) |
24 (68.6%) |
25 (69.4%) |
49 (69.0%) |
| Soft stool constipation (with/without perianal rash due to infection) |
12 (34.3%) |
17 (47.2%) |
29 (40.8%) |
| Faltering growth after the dietary inclusion of cow’s milk protein |
13 (37.1%) |
11 (30.6%) |
24 (33.8%) |
| Extended periods of diarrhea with a negative stool examination |
8 (22.9%) |
9 (25.0%) |
17 (23.9%) |
| Blood in stool |
10 (28.6%) |
5 (13.9%) |
15 (21.1%) |
| Endoscopically confirmed eosinophilic enteropathy |
0 |
0 |
0 |
| |
|
|
|
| Skin symptoms |
|
|
|
| Eczema |
16 (45.7%) |
21 (58.3%) |
37 (52.1%) |
| Urticaria |
3 (8.6%) |
4 (11.1%) |
7 (9.9%) |
| |
|
|
|
| Respiratory symptoms |
|
|
|
| Sneezing/nasal congestion |
9 (25.7%) |
12 (33.3%) |
21 (29.6%) |
| Wheezing |
5 (14.3%) |
5 (13.9%) |
10 (14.1%) |
| Conjunctivitis |
1 (2.9%) |
3 (8.3%) |
4 (5.6%) |
| Dyspnea |
1 (2.9%) |
1 (2.8%) |
2 (2.8%) |
| Stridor |
1 (2.9%) |
1 (2.8%) |
2 (2.8%) |
| Dysphonia |
0 |
0 |
0 |
| Aphonia |
0 |
0 |
0 |
| |
|
|
|
| Other symptoms |
|
|
|
| Hypotension for age |
0 |
0 |
0 |
| |
|
|
|
| Predominant complaint/stratification factor |
|
|
|
| Skin symptoms |
4 (11.4%) |
3 (8.3%) |
7 (9.9%) |
| Gastrointestinal symptoms |
31 (88.6%) |
33 (91.7%) |
64 (90.1%) |
