Table 5.

Summary of covariates that had a statistically significant impact on skin and nipple fluorescent intensity and tissue necrosis.*

Covariate	Impact	p-value
Perfusion – Skin Flap
Smoking	↓ 12.5%	0.02
MAP	↓ 1.5% for every 5 mmHg	0.04
IMF incision	↓ 17.5%	0.001
Perfusion - Nipple
Smoking	↓ 13%	0.03
Specimen weight	3.4% for every 100 gram increase	0.02
Tissue Necrosis
Operative time	OR 1.1 per additional 10 minutess	0.03
Whole breast fluorescent intensity	OR 2.0 per 10% decrease in perfusion	0.007
Smoking	OR 6.7 for smokers	0.03
KPS	OR 4.5 for every 10 unit decrease	0.01

The multivariate model for fluorescent intensity included smoking, age, specimen weight, laterality, MAP, incision, and operative time. For necrosis it included fluorescent intensity, smoking, age, specimen weight, mean arterial pressure during surgery, laterality, incision type and operative time.