Table 3.
Systemic and cerebral hemodynamics in patients responders–responders (RR) versus responders–non-responders (RnR) in the sepsis group
| RR n = 23 |
RNR n = 15 |
p | |
|---|---|---|---|
| Baseline | |||
| CO (l min−1) | 5.7 (4 to 6.8) | 4.9 (3.5 to 6.7) | 0.4288 |
| SV (ml) | 54 (38 to 71) | 52 (41 to 75) | 0.8076 |
| HR (min−1) | 108 (89 to 124) | 93 (71 to 101) | 0.0374 |
| SAP (mmHg) | 99 (88 to 110) | 107 (86 to 121) | 0.2382 |
| DAP (mmHg) | 51 (44 to 58) | 53 (50 to 57) | 0.5107 |
| MAP (mmHg) | 64 56 to 74) | 70 (62 to 77) | 0.1685 |
| PP (mmHg) | 45 (34 to 60) | 49 (42 to 69) | 0.2382 |
| PSV (cm s−1) | 81 (63 to 108) | 101 (82 to 107) | 0.5205 |
| EDV (cm s−1) | 36 (25 to 42) | 33 (26 to 36) | 0.4287 |
| FC test | |||
| ∆CO (%) | 27 (18 to 35)* | 27 (14 to 29)* | 0.3323 |
| ∆SV (%) | 39 (20 to 44)* | 25 (14 to 29)* | 0.0993 |
| ∆HR (%) | − 5 (− 9 to 0)* | − 2 (− 4 to 3) | 0.0928 |
| ∆SAP (%) | 30 (14 to 39)* | 1 (− 1 to 5) | < 0.0001 |
| ∆DAP (%) | 12 (7 to 18)* | 0 (− 4 to 3) | < 0.0001 |
| ∆MAP (%) | 25 (13 to 29)* | 0 (− 4 to 4) | < 0.0001 |
| ∆PP (%) | 52 (22 to 67)* | 4 (− 1 to 14) | < 0.0001 |
| ∆PSV (%) | 24 (11 to 30)* | 10 (− 2 to 33)* | 0.1348 |
| ∆EDV (%) | 17 (14 to 42)* | 18 (5 to 42)* | 0.7400 |
Quantitative values were expressed as median (25th–75th). Statistical tests: intragroup: nonparametric Wilcoxon test; intergroup: nonparametric Mann–Whitney test
CO cardiac output, SV stroke volume, HR heart rate, SAP systolic arterial pressure, DAP diastolic arterial pressure, MAP mean arterial pressure, PP pulse pressure, PSV pic systolic velocity, EDV end diastolic velocity, FC fluid challenge, RR responders responders, RNR responders non-responders
*Significant difference after FL compared with baseline