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. 2018 May 30;596(13):2565–2579. doi: 10.1113/JP275604

Figure 4. Effects of Parkin knockout on mitochondrial biogenesis and content in skeletal muscle.

Figure 4

A, quantification of the mRNA content of several proteins involved in the mitochondrial biogenesis program in skeletal muscle homogenates from Park2−/− and Park2+/+ mice. B–G, quantification of the content of PGC‐1a (n = 4 per group), PGC‐1b (B) (n = 4 per group), TOMM70 (C) (n = 4 per group), VDAC (D) (n = 4 per group), COX I (E) (n = 7 or 8 per group), COX IV (F) (n = 4 per group) and HSP60 (G) (n = 4 per group) in skeletal muscle of Park2−/− and Park2+/+ mice by western blotting (n = 4 per group). * P < 0.05.