Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2018 Jun 28;9:2529. doi: 10.1038/s41467-018-04839-9

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s) 2018

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

PMC Copyright notice

Fig. 7 — Enhanced representation of target stimuli in a range of auditory Go/No-Go tasks. Each line of four panels represent the same analysis for all four tasks; statistics are given in order of appearance in the figure. a, e, i, m Projection onto the decoding axis determined during the sound period of trial-averaged reference (blue) and target (ref) activity during the passive (dark colors) and the engaged (light colors) sessions. A baseline value computed from spontaneous activity was subtracted for each neuron, so that the origin corresponds to the projection of spontaneous activity (shown by black line). Note that the target-driven activity is further from the baseline in the engaged state and the reference-driven activity is closer. The periods used to construct the decoding axis are shaded in gray. Error bars represent 1 std (cross-validation n = 400). b, f, j, n Index of target enhancement induced by task engagement based on projections using the decoding axis determined during the sound. In green, same index computed instead by giving the same weight to all units. The difference between the green and black curved indicates that the change in asymmetry induced by task engagement cannot be detected using the population averaged firing rate alone. Error bars represent 1 std (cross-validation n = 400). c, g, k, o Modulation index of each unit for spontaneous firing rate after exclusion of lick-related units. Error bars are 95% CI (one-sample two-sided Wilcoxon signed-rank test with mean 0, n = 277, zval = 6.35, p = 2.1e-10; n = 161, zval = 7.22, p = 5.4e-13; n = 99, zval = 1.01, p = 0.30; n = 520, zval = −0.78, p = 0.47; ***p < 0.001). d, h, l, p Comparison of reference/target asymmetry for evoked responses in different states relative to different baselines given by passive or engaged spontaneous activity. Reference/target asymmetry is the difference of the distance of target and reference projected data to a given baseline. We examine three cases: (i) passive evoked responses, distances calculated relative to engaged spontaneous activity; (ii) engaged evoked responses, distances calculated relative to passive spontaneous activity; (iii) engaged evoked responses, distances calculated relative to engaged spontaneous activity. In all three cases, the engaged decoding axis was used for projections. Error bars represent 95% confidence intervals (n = 400 cross-validations; p(col1,col3) = 0.29 and p(col2,col3) < 0.0025; p(col1,col3) = 0.38 and p(col2,col3) < 0.0025; p(col1,col3) < 0.0025 and p(col2,col3) = 0.16; p(col1,col3) < 0.0025 and p(col2,col3) = 0.92; **p < 0.01)