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. 2018 Jun 22;9:1461. doi: 10.3389/fimmu.2018.01461

Figure 3.

Figure 3

Inducible T-cell co-stimulator promotes Th17 cell differentiation. Bone marrow transplantation (BMT) was setup as described in Figures 1B–E. 60 days after BMT, recipient spleens were harvested and processed for flow cytometry. (A) Representative histograms plots and mean percentage of CD44 gated on H-2Kb+CD4 and CD8 T cells are shown, n = 8 mice/group. Representative contour plots of individual mice (B) and bar graphs of mean percentage (C) of IFN-γ+, IL-4/5+, and IL-17+ on gated H-2Kb+CD4+ cells are shown, n = 6–8 mice/group. Summary of mean percentage of IFN-γ+, IL-4/5+, and IL-17+ on gated H-2Kb+CD4+ cells are shown over time (D), n = 3–4 mice per group. *p < 0.05.