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. 2018 Jun 22;12:47. doi: 10.3389/fncir.2018.00047

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Copyright © 2018 Rho, Kim and Lee.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Comparing anatomical selectivity of BF cholinergic and LC noradrenergic projections to the cortex in rodents. (A) Projection patterns of BF cholinergic and LC noradrenergic projections to the primary sensory cortices in a mouse brain. The neurons in the NB and the HDB show selective innervation to the primary sensory cortices whereas LC neurons show diverging innervation (Kim et al., 2016). (B) Projection patterns of the BF and the LC neurons to the PFC in a rat brain. The NB neurons send more diverging projections than the LC neurons (Chandler et al., 2013).