Skip to main content
. 2018 Jun 22;9:659. doi: 10.3389/fphar.2018.00659

Table 1.

Summary of clinical trials included in meta-analysis.

Trial/year Sample size Mean age (men/women) Patient entry criteria Experiment group Control group Treatment duration Outcome measures
Zhou, 2010 Exp:63 61–87 NP Ginkgo biloba tablet 480 mg/d Atorvastatin 20 mg/d 26 weeks TG, TC, LDL-C, HDL-C
Con:62 (66/59) LDL-C ≥ 3.4 mmol/L, TG ≥ 1.7 mmol/L LDL-C ≥ 3.4 mmol/L, TG ≥ 1.7 mmol/L
Guo and Ju, 2011 Exp:40 46–79 TC ≥ 5.72 mmol, Ginkgo biloba pill 480 mg/d + Atorvastatin 20 mg/d 24 weeks TC, LDL-C, HDL-C, AE
Con:39 (44/36) LDL-C ≥ 3.64 mmol/L, and/or HDL-C ≤ 1.04 mmol/L atorvastatin 20 mg/d
Zhong and Bao, 2011 Exp:30 39–78 TC ≥ 5.2 mmol, Ginkgo biloba tablet 240 mg/d Atorvastatin 10 mg/d 6 weeks TG, TC, LDL-C, HDL-C
Con:29 (29/30) LDL-C ≥ 3.64 mmol/L, TG ≥ 1.7 mmol/L + atorvastatin 10 mg/d
Lin et al., 2011 Exp:32 28–76 TC ≥ 5.2 mmol, Ginkgo biloba tablet 240 mg/d Atorvastatin 10 mg/d 6 weeks TG, TC, LDL-C, HDL-C, AE
Con:32 (35/29) LDL-C ≥ 3.4 mmol/L, TG ≥ 1.7 mmol/L + atorvastatin 10 mg/d
Jin et al., 2012 Exp:33 36–71 TC ≥ 5.2 mmol, Ginkgo biloba tablet 240 mg/d Rosuvastatin 10 mg/d 4 weeks TG, TC, LDL-C, HDL-C, AE
Con:32 (36/29) LDL-C ≥ 3.64 mmol/L, TG ≥ 1.7 mmol/L + rosuvastatin 10 mg/d
Ren, 2012 Exp:41 Exp:54.8 ± 3.2/(NP) TC ≥ 5.2 mmol, Ginkgo biloba tablet 576 mg/d Simvastatin 20 mg/d 8 weeks TG, TC, LDL-C, HDL-C
Con:41 Con:59.1 ± 4.6/(NP) LDL-C ≥ 3.4 mmol/L, TG ≥ 1.7 mmol/L + simvastatin 20 mg/d
Zhu, 2012 Exp:65 42–78 TC ≥ 5.752 mmol, Ginkgo biloba capsule Simvastatin 10 mg/d 6 weeks TG, TC, LDL-C, HDL-C
Con:65 (62/58) LDL-C ≥ 3.64 mmol/L, and/or HDL-C ≤ 1.04 mmol/L, TG ≥ 1.7 mmol/L 120 mg/d + simvastatin 20 mg/d
Xu, 2013 Exp:30 47–80 TC ≥ 5.2 mmol, Ginkgo biloba tablet Simvastatin 20 mg/d 8 weeks TG, TC, LDL-C, HDL-C
Con:30 (37/23) LDL-C ≥ 3.4 mmol/L, TG ≥ 1.7 mmol/L 240 mg/d + simvastatin 20 mg/d

Exp, experiment; Con, control; TGs, triglycerides; TC, total cholesterol; LDL-C, low density lipoprotein cholesterol; HDL-C, high-density lipoprotein cholesterol.