Table 1: Baseline characteristics between patients with and without diagnosis of HCC
| Total (n = 452) | HCC (n = 150) | Non-HCC (n = 302) | p-value | ||||||
| Age (years), mean ± SD | 59.2 ± 9.8 | 62.4 ± 10.2 | 57.6 ± 9.2 | <0.001 | |||||
| Male sex, n (%) | 279 (61.7) | 90 (60) | 189 (62.6) | 0.595 | |||||
| Cirrhosis, n (%) | 350 (77.4) | 135 (90) | 215 (71.2) | <0.001 | |||||
| Underlying liver disease, n (%) | |||||||||
| • Chronic hepatitis B (CHB) | 243 (53.8) | 63 (42) | 180 (59.6) | ||||||
| • Chronic hepatitis C (CHC) | 117 (25.9) | 53 (35.3) | 64 (21.2) | ||||||
| • CHB/CHC coinfection | 7 (1.5) | 4 (2.7) | 3 (1) | ||||||
| • Alcoholic cirrhosis | 33 (7.3) | 8 (5.3) | 25 (8.3) | ||||||
| • CHB/alcoholic | 3 (0.7) | 1 (0.7) | 2 (0.7) | ||||||
| • CHC/alcoholic | 4 (0.9) | 3 (2) | 1 (0.3) | ||||||
| • CHB/CHC/alcoholic | 1 (0.2) | 1 (0.7) | 0 | ||||||
| • Nonalcoholic steatohepatitis | 16 (3.5) | 4 (2.7) | 12 (4) | ||||||
| • Autoimmune hepatitis | 3 (0.7) | 2 (1.3) | 1 (0.3) | ||||||
| • Primary biliary cholangitis | 3 (0.7) | 2 (1.3) | 1 (0.3) | ||||||
| • Wilson disease | 2 (0.4) | 0 | 2 (0.7) | ||||||
| • Hemochromatosis | 1 (0.2) | 1 (0.7) | 0 | ||||||
| • Methotrexate-induced cirrhosis | 1 (0.2) | 1 (0.7) | 0 | ||||||
| • Cryptogenic cirrhosis | 18 (4) | 7 (4.7) | 11 (3.6) | ||||||
| Screening US positive, n (%) | 353 (78.1) | 122 (81.3) | 231 (76.5) | ||||||
| Screening AFP positive (>20 lU/mL), n (%) | 82 (18.1) | 54 (36) | 28 (9.3) | <0.001 |