Table 5: Correlation of AFP and IL-6 levels in a total of 130 liver cirrhosis patients (55 with HCC, 75 w/o HCC) with Child scores, etiology of cirrhosis, TNM classification, extrahepatic spread, and portal vein invasion
| AFP (median range) | IL-6 (median range) | p-value (AFP) | p-value (IL-6) | ||||||||
| Child score | Child A | 15.8 (0.6-1,200) | 5.3 (0.16-78.50) | 0.191 | 0.643 | ||||||
| Child B | 8.3 (0.8-12,100) | 4.2 (0.3-78) | |||||||||
| Child C | 3.1 (0.6-12,100) | 6.06 (0.6-78) | |||||||||
| Cirrhosis etiology | HBV (n = 57) | 15.1 (0.6-12,100) | 5.7 (0.3-78.5) | 0.396 | 0.126 | ||||||
| HCV (n = 29) | 13.6 (0.7-3,674) | 8.7 (0.8-41) | |||||||||
| HBV + HCV (n = 3) | 4.3 (0.7-40) | 2 (0.4-12) | |||||||||
| Delta (n = 8) | 10.3 (1.1-1,421) | 4.3 (0.6-78) | |||||||||
| OIH (n = 2) | 1.2 | 1.22 | |||||||||
| Wilson (n = 1) | 2.28 | 1.01 | |||||||||
| Kriptojenik (n = 23) | 3.04 (0.6-12,100) | 3.1 (0.3-78.5) | |||||||||
| Alkol (n = 7) | 3.4 (1.8-5.6) | 2.2 (0.8-6.2) | |||||||||
| TNM | Evre I (n = 3) | 14.91 (1.1-18.7) | 4.2 (1.2-4.6) | 0.278 | 0.011 | ||||||
| Evre II (n = 20) | 40.8 | (3.4-11,798) | 9.8 (0.8-78.5) | ||||||||
| Evre III (n = 14) | 57.5 | (2.5-31,928) | 7.9 (0.9-25.9) | ||||||||
| Evre IV (n = 38) | 281.9 (80-12,100) | 17.7 (0.8-78.5) | |||||||||
| Extrahepatic spread | Yes (n = 12) | 40.5 (0.8-13,280) | 19.9 (1-48.5) | 0.164 | 0.312 | ||||||
| No (n = 63) | 102.8 (1-12,100) | 10.8 (0.8-78.5) | |||||||||
| Prediction of portal vein invasion | Yes (n = 23) | 111 (1.7-12,100) | 21 (0.5-78.5) | 0.022 | 0.09 | ||||||
| No (n = 52) | 34.5 (0.8-6,050) | 9.8 (0.8-78.5) |