Table 2.

Considerations for implementation of new diagnostics (experience drawn from Xpert MTB/RIF implementation [66, 67])

Build a good team	Trainers (technical, clinical), program managers, data analysts, TB and HIV specialists, R&D scientists
Develop models and trend analyses	Cost, forecast [68, 69], program interface [70], socioeconomic trends [71]
Maintain networks	WHO, new developers, NDOH – stakeholders, funders, clinical lab interface
Sustain quality management system	* EQA [72], Connectivity [73–75], manage assay change over, SOPs, infrastructure, HR, stock control, algorithms
Monitoring and evaluation	Investment case update, epidemiology and surveillance
Align Parallel programs	Correctional facilities, children, EPTB, rural/remote communities through mobile/POC
Integration of services	Platform optimization and service refinement
Linkage to care	Maximize laboratory LIS for faster data streams (SMS printers, m-health)

^*some of the 12 components of the quality assurance model mentioned