Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2018 Jun 22;8:209. doi: 10.3389/fcimb.2018.00209

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2018 Martínez-Castillo, Pacheco-Yepez, Flores-Huerta, Guzmán-Téllez, Jarillo-Luna, Cárdenas-Jaramillo, Campos-Rodríguez and Shibayama.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

PMC Copyright notice

Possible effects of flavonoids in the regulation of biochemical and immunological responses against amebiasis. (A) Recruitment of neutrophils and macrophages by E. histolytica promoting the synthesis and production of pro-inflammatory cytokines and oxidative mediators. E. histolytica presents detoxifying enzymes. (B) Possible mechanisms of the flavonoids as direct scavenger of ROS, ONOO⁻, and NO, enhancer of CAT, SOD, and GPx enzymes and regulation of inflammation via STAT and NF-κB. Effect of the flavonoids in neutrophils (MPO production), macrophages (decrease of inflammatory mediators), and E. histolytica trophozoites (direct damage in different molecular targets).