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. 2018 Jun 28;38(14):e00590-17. doi: 10.1128/MCB.00590-17

FIG 7.

FIG 7

Model of IRS2 function. Upstream receptor activation stimulates dynamic intramolecular interactions within IRS2 that facilitate recruitment of PI3K and BMP2K to enhance invasion. SS, disulfide bond; P, tyrosine phosphorylation site.