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TOR enhances PIC formation (and hence transcription) at the promoters of the ADH1, PHO84, and PGK1 genes. (A) TOR facilitates the recruitment of TBP to the core promoters of the ADH1, PHO84, and PGK1 genes. Yeast cells were grown as for Fig. 1A. (B) TOR facilitates recruitment of Rpb1p to the core promoters of the ADH1, PHO84, and PGK1 genes. (C) RT-PCR analysis. Transcription of the ADH1, PHO84, and PGK1 genes is impaired following rapamycin inhibition of TOR.
