Figure 2.

Chromothripsis and copy number aberrations plot from CTLPScanner. Highlighted chromothripsis-like regions are shown in the left side of the graph. The x and y axes represent genomic positions and log R ratio of segments, respectively. The orange lines represent areas of copy number gain; blue lines, areas of copy number loss; zero lines, no gain/loss; orange rectangles, identified chromothripsis regions. Histograms on the right side show the number of copy number segment change events. Chr, chromosome; HG-PanIN, high-grade pancreatic intraepithelial neoplasia; LG-PanIN, low-grade pancreatic intraepithelial neoplasia.