Table 1.
Socio-demographic Characteristics of adults with Haematologic malignancies seen at the Jos University Teaching Hospital, Nigeria between 2005 and 2015 (n=60)
| Socio-demographic
characteristics. | |
|---|---|
| Variable | n (%) |
| Mean Age, years | 43+17 |
| Sex | |
| Female | 23 (38.3) |
| Male | 37 (61.7) |
| Education attained | |
| No formal education | 7 (14.0) |
| Primary | 7 (14.0) |
| Secondary | 17 (34.0) |
| Tertiary | 19 (38.0) |
| Marital status | |
| Single | 15 (25.9) |
| Married | 38 (65.5) |
| Widowed | 4 (6.9) |
| Divorced | 1 (1.7) |
| Occupation | |
| Unemployed | 20 (33.9) |
| Self-employed | 30 (50.8) |
| Civil servant | 9 (15.3) |
| Clinical characteristics | |
| Disease group | |
| Leukemia | 31 (51.7) |
| Lymphoma | 27 (45.0) |
| Myeloma | 2 (3.3) |
| Disease stage | |
| Early | 17 (28.8) |
| Advanced | 42 (71.2) |
| Presenting features | |
| Lymph node enlargement | 36 (63.2) |
| Fever/Pyrexia | 28 (48.3) |
| Splenomegaly | 27 (47.4) |
| Hepatomegaly | 24 (42.1) |
| Abdominal mass | 12 (21.1) |
| Epistaxis | 3 (5.4) |
| Gum bleeds | 2 (3.6) |
| Laboratory indices | |
| Median Haematocrit (IQR) | 28 (21–35) |
| Median TWCC (IQR) | 30,000 (6000–110,000) |
| Median platelet (IQR) | 204,500 (110,000–350,000) |
| Median neutrophils (%)* | 40 (18–59) |
| Median lymphocytes (%)* | 31.5 (12–69) |
| Proportion with abnormal laboratory values | |
| Anaemia | 30 (50.0) |
| Leucocytosis | 33 (55.0) |
| Thrombocytopaenia | 9 (15.0) |
| HIV status | |
| Positive | 3 (5.2) |
| Negative | 33 (56.9) |
| Unknown | 22 (37.9) |
| Follow up data | |
| Median follow-up time,(days), IQR | 182 (50–737) |
| Person-time contributed (days) | 25, 994 |
| Received cytotoxic therapy (%) | 50 (86.2) |
| Regimen received (%): | |
| Non-purineanalogue-alkylating agent based combination | 19 (38.0) |
| Single-agent alkylator therapy (+/− steroid) | 16 (32.0) |
| Antibody or other therapy | 15 (30.0) |
| Outcome (%) | |
| Alive | 56 (93.3) |
| Died | 4 (6.7) |
| Overall survivial (95% CI) | 84.3 (58.1–94.7) |
TWCC-Total white cell count
*
Subset of TWCC
NB: Compared to patients alive at the time of censoring data, patients who died were similar in age (p=0.84), sex (p=0.53) disease stage (p=0.20) and Haematocrit status (p=0.85), platelet counts (p=0.85) and follow-up time (p=0.62)