Table 2.

Distribution of SN Gangliosides in Male and Female Control and PD Subjects.

Gangliosides	Males		Females
	Ctl, n=10	PD, n=7	Ctl, n=8	PD, n=5
GM3	3.2 ± 0.3	3.2 ± 0.3	1.8 ± 0.6	1.7 ± 1.1
GM2	5.7 ± 0.5	4.9 ± 0.3	3.7 ± 1.5	2.0 ± 1.3
GM1	41.7 ± 2.2	37.4 ± 1.8	37.1 ± 3.6	36.9 ± 4.2
GD3	19.4 ± 1.7	18.4 ± 1.5	18.8 ± 2.4	19.2 ± 2.1
GD1a	78.1 ± 6.7	52.2 ± 3.6**	51.3 ± 11.4	50.5 ± 11.3
GT1a	7.9 ± 0.6	7.2 ± 0.6	7.1 ± 0.4	7.7 ± 0.5
GD1b	42.3 ± 2.6	33.7 ± 2.1*	39.9 ± 1.5	42.3 ± 3.0
GT1b	44.3 ± 3.3	30.3 ± 1.9**	38.5 ± 1.54	37.9 ± 3.0
GQ1b	10.2 ± 1.1	7.8 ± 0.6	10.5 ± 0.6	10.6 ± 0.5

Note. All values are expressed as µg/100 mg dry weight sialic acid/mg dry weight and represent the mean ± SEM. The asterisks indicate significant difference from controls of the same sex at *p < .05 and at **p < .01 as determined by the two-tailed t test. SN = substantia nigra.