Table 1.
Behavioral and electrographic alterations observed after intrahippocampal injection of Fractions I, II, III and IV (2 µg/µL) or Ringer’s solution (1 µL, control group). WDS, wet dog shakes.
| Alteration Observed | Fraction I n = 6 | Fraction II n = 6 | Fraction III n = 6 | Fraction IV n = 6 | Ringer n = 6 |
|---|---|---|---|---|---|
| Prostration | 33% | 33% | 17% | 17% | 0% |
| Respiratory difficulty | 17% | 50% | 0% | 0% | 0% |
| Locomotor difficulty | 0% | 50% | 0% | 0% | 0% |
| Salivary and lachrymal Secretions | 17% | 33% | 0% | 0% | 0% |
| Myoclonus | 0% | 83% | 0% | 0% | 0% |
| WDS | 33% | 83% * | 0% | 0% | 0% |
| Spikes | 33% | 83% * | 0% | 0% | 0% |
| Epileptiform discharges | 33% | 83% * | 0% | 0% | 0% |
The statistical analysis was performed using Fisher’s exact test, * p < 0.05.