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. 2018 Jun 14;10(6):326. doi: 10.3390/v10060326

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© 2018 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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RNA viral load quantification by qRT-PCR (A) according to the disease outcome (non-fatal: n = 40; fatal: n = 40) p = 0.06 by using t test; (B) by type of infection (primary: n = 24 versus secondary: n = 45) using t test; (C) in primary non-fatal (n = 8) versus fatal (n = 16) cases, * p < 0.01 using t test; (D) in secondary non-fatal (n = 23) versus fatal (n = 22) cases, * p < 0.01 using t test; (E) in the analysis of DENV serotype regardless of the disease outcome (n = 80), * p < 0.01 by ANOVA test; (F) in the analysis of the distinct DENV serotypes according to the disease outcome (fatal: n = 10 and non-fatal/serotype) using t test. For DENV-2 fatal versus non-fatal cases, * p < 0.01, and for DENV-3 fatal versus non-fatal cases, * p < 0.01.

RNA viral load quantification by qRT-PCR (A) according to the disease outcome (non-fatal: n = 40; fatal: n = 40) p = 0.06 by using t test; (B) by type of infection (primary: n = 24 versus secondary: n = 45) using t test; (C) in primary non-fatal (n = 8) versus fatal (n = 16) cases, * p < 0.01 using t test; (D) in secondary non-fatal (n = 23) versus fatal (n = 22) cases, * p < 0.01 using t test; (E) in the analysis of DENV serotype regardless of the disease outcome (n = 80), * p < 0.01 by ANOVA test; (F) in the analysis of the distinct DENV serotypes according to the disease outcome (fatal: n = 10 and non-fatal/serotype) using t test. For DENV-2 fatal versus non-fatal cases, * p < 0.01, and for DENV-3 fatal versus non-fatal cases, * p < 0.01.