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CXCR4 Affinities (IC50) of the Novel [natF]AlF-NOTA and [natF]AlF-NODA-NCS-Pentixather Analogs, the Reference [natGa]Pentixafor, and the Corresponding Uncomplexed Peptides
| Compound | IC50 [nM] |
|---|---|
| Pentixafor | 102 ± 16 |
| [natGa]pentixafor | 24.8 ± 2.5 |
| NOTA-pentixather | 27.5 ± 2.1 |
| [natF]AlF-NOTA-pentixather | 17.9 ± 0.2 |
| NODA-NCS-pentixather | 100 ± 15 |
| [natF]AlF-NODA-NCS-pentixather | 302 ± 77 |
