Table 3.
Multiple linear regression analysis with Child–Turcotte–Pugh score as the dependent variable in patients with liver cirrhosis after adjusting for potential confounders.
| Parameters | Covariate Model | β (Standard Error) | p Value |
|---|---|---|---|
| NLR | Confounders 1 | 0.095 (0.084) | 0.264 |
| GSH + confounders | 0.101 (0.077) | 0.197 | |
| GSH + NLR × GSH + confounders | −0.264 (0.221) | 0.237 | |
| hs-CRP | Confounders | 0.074 (0.036) | 0.065 |
| GSH + confounders | 0.099 (0.035) | 0.007 | |
| GSH + hs-CRP × GSH + confounders | −0.275 (0.154) | 0.079 | |
| GSH | Confounders | −0.014 (0.005) | 0.007 |
| NLR + confounders | −0.016 (0.004) | <0.001 | |
| hs-CRP + confounders | −0.017 (0.005) | <0.001 | |
| NLR + NLR × GSH + confounders | −0.030 (0.009) | 0.002 | |
| hs-CRP + hs-CRP × GSH + confounders | −0.021 (0.005) | <0.001 | |
| NLR × GSH | NLR + GSH + confounders | 0.005 (0.003) | 0.084 |
| hs-CRP × GSH | hs-CRP + GSH + confounders | 0.004 (0.001) | 0.016 |
| GSSG | Confounders | −0.002 (0.002) | 0.272 |
| GSH/GSSG ratio | Confounders | −9.741 (3.468) | 0.007 |
n = 75. β, regression coefficient. NLR, neutrophil-to-lymphocyte ratio; hs-CRP, high sensitivity C-reactive protein; GSH, glutathione; GSSG, glutathione disulfide. 1 Adjusted for age, sex, body mass index, smoking and drinking status, hepatitis, and silymarin use.