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Schematic representation of the EV-A71 genome (7.4 Kb). The position of the VPg primer is shown at the 5′ NTR end of the genome; the Open Reading Frame (ORF) contains the structural viral protein P1 which is cleaved to yield VP1, VP2, VP3 and VP4, and non-structural viral proteins P2 (cleaved to yield 2A, 2B and 2C) and P3 (cleaved to yield 3A, 3B, 3C and 3D). The 3′ NTR end of the genome contains the poly (A) tail.
