Table 2.
Fold changes in gene expression for selected C. jejuni NCTC 11168 genes at 30, 60, and 120 min post NCTC 12673 phage addition compared to mock-infected controls at each time point.
| Fold Change (P-Value) a | ||||
|---|---|---|---|---|
| Gene | Annotation | 30 min (p) | 60 min (p) | 120 min (p) |
| Multi-drug efflux pump CmeABC | ||||
| cmeA | Periplasmic fusion protein CmeA (multidrug efflux system CmeABC) | 2.6 (<0.01) | NS | 1.99 (<0.01) |
| cmeB | Inner membrane efflux transporter CmeB (multidrug efflux system CmeABC) | 2.09 (<0.01) | NS | 2.14 (<0.01) |
| cmeC | Outer membrane channel protein CmeC (multidrug efflux system CmeABC) | 2.04 (<0.01) | NS | 2.02 (<0.01) |
| Oxidative stress and iron metabolism | ||||
| katA | Catalase | 3.1 (<0.01) | NS | 3.42 (<0.01) |
| chuA | Haemin uptake system outer membrane receptor | 7.73 (<0.01) | 4.9 (<0.01) | 6.84 (<0.01) |
| chuB | Putative haemin uptake system permease protein | 3.02 (<0.01) | NS | 1.8 (0.02) |
| chuC | Putative haemin uptake system ATP-binding protein | NS | NS | 2.49 (0.05) |
| chuD | Putative haemin uptake system periplasmic haemin-binding protein | 3.9 (<0.01) | 2.73 (0.02) | 3.31 (<0.01) |
| chuZb | Iron-responsive cellular heme oxygenase | 3.34 (<0.01) | 3.25 (<0.01) | 2.47 (<0.01) |
| Uncharacterized operon cj0423–cj0425 | ||||
| cj0423 | Putative integral membrane protein | 5.73 (<0.01) | 3.36 (<0.01) | 16.14 (<0.01) |
| cj0424 | Putative acidic periplasmic protein | 9.95 (<0.01) | 10.51 (<0.01) | 12.75 (<0.01) |
| cj0425 | Putative periplasmic protein | 9.01 (<0.01) | 9.1 (<0.01) | 10.39 (<0.01) |
a Genes were considered differentially expressed when the false discovery rate-corrected p-value < 0.05. NS = not statistically significant, cells were left blank. b Annotation updated according to [57].