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. 2018 Jun 1;10(6):712. doi: 10.3390/nu10060712

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© 2018 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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SM70EE administration upregulates thermogenic genes in BAT of HFD-fed mice and in inducible WAT cells. (a) BAT from mice treated with SM70EE was analyzed for the expression of BAT-specific proteins. (b) SVF cells were differentiated into white adipocytes, as described in the Materials and methods. Protein expression of browning factors was measured in primary WAT adipocytes. All data are presented as mean ± SD (n = 6). Values with different letters are significantly different, p < 0.05 (a > b > c > d > e).