Table 3.
Reference | [42] | [43] | [34] | [35] | [36] | [37] | [38] | [39] | [40] | [41] | |
---|---|---|---|---|---|---|---|---|---|---|---|
Taxa/Method | YF | PR | Ill Miseq | Ill Hiseq | Ro | ||||||
Unclassified Firmicutes (unclass.) | < | ||||||||||
Firmicutes unspecified (unspec.) | > | ||||||||||
Lactobacillaceae unspec. | > | < | < | < | |||||||
Lactobacillus, m = mucosae, g = gassero, c = caseo, f = fermentum, re = reuteri, ru = ruminis, |
<(+g, c, f, re, ru) | <(+m) | < | ||||||||
Enterococcaceae unspec | > | < | < | ||||||||
Enterococcus | < | ||||||||||
Ruminococcaceae unclassified | < | ||||||||||
Ruminococcaceae OTU 4439469 | <(o1) | < | |||||||||
Ruminococcus, b = bromii, c = callidus | <(b) | >(c) | > | ||||||||
Papillibacter c = cinnamivorans | <(c) | ||||||||||
Faecalibacterium, p = prausnitzi | >(p) | > | >(o2) | > | |||||||
Lachnospiraceae unclassified | >(o3) | ||||||||||
Lachnospiraceae unspec | > | ||||||||||
Roseburia | >(+o2) | > | |||||||||
Coprococcus, e = eutactus | >(e) | >(o1) | > | ||||||||
Blautia, g = glucerasea | >(g) | >(+o1) | > | > | |||||||
Dorea, l = longicatea | >(+l) | ||||||||||
Catabacteriaceae Catabacter, h = honkongenesis | <(+h) | ||||||||||
Clostridiaceae Anaerotruncus | < | ||||||||||
Clostridium, c = coccoides, s = saccharolyticum | >(c) | >(s) | |||||||||
Eubacteriaceae, [candidatus stoquefichus massiliensis] | > | ||||||||||
Erysipeltrichoceae unspec. | < | ||||||||||
Eubacterium, b = biforme | >(b) | ||||||||||
Christensenellaceae unclass. | < | ||||||||||
unspec | < | ||||||||||
Christensenella, m = minuta | <(+m) | ||||||||||
Oscillospiraceae, oscillospira | < | < | |||||||||
Streptococcaceae, unspec | < | ||||||||||
Streptococcus | < | ||||||||||
Acidaminococcaceae, Acidaminococcus | < | ||||||||||
Veillonellaceae unspec | < | ||||||||||
Veillonellaceae, Megamonas | < | ||||||||||
Veillonellaceae Megasphera | < | ||||||||||
[Tissierellaceae] unspec. | < |
This table shows the significant relative changes in the Firmicutes phyla between PD patients (PD) and healthy controls (HC), that were assessed by the 10 summarized Parkinson’s disease studies. > symbolizes a higher abundance in HC when compared to PD; < symbolizes a lower abundance in HC when compared to PD; An empty cell symbolizes, that no significant change in PD compared to HC was found with the chosen methodological approach. o1, 2, 3 symbolize, that one, two, or three OTUs of the taxa were significantly changed in PD compared to HC; + indicates that a change in PD compared to HC on the genus and on the species level was found. The methods used by the studies are Yakult Intestinal Flora-SCAN (YF), 96-well block of the ABI PRISM 7900HT Sequence Detection System (PR), Illumina Miseq sequencing (Ill Miseq), Illumina Hiseq sequencing (Ill Hiseq), Roche 454 GS FLX Titanium sequencing (Ro).