Table 2.
Intracardiac/intravenous models.
Study | Cell Line Used | Cancer Type | Animal Used | Methodology and Outcomes |
---|---|---|---|---|
Le Gall et al. [59] | B02 | Breast | Nude mice | B02 cells were injected into the tail vein |
Yoneda et al. [63] | MDA-MB-231 | Breast | Nude Mice | Spread was mostly to the bone, but occasionally to adrenal glands, ovary, and brain 3–4 weeks after inoculation. |
Henriksen et al. [64] | MT-1 | Breast | Nude rats | N/A |
Yi et al. [65] | MCF-7 | Breast | Nude mice | N/A |
Canon et al. [66] | MDA-MB-231 | Breast | Nude mice | Cells were luciferase labeled |
Wu et al. [67] | LNCaP, C4-2, or PC3 | Prostate | Athymic or SCID mice | C4-2 cells demonstrated a preference to spinal and lymph node metastases, PC3 cells developed distant widespread metastases, and LNCaP did not demonstrate any metastasess. |