Table 4.
Association between air pollution exposure and questionnaire outcomes.
| Questionnaire Outcome | PM2.5 | Ozone | ||||
|---|---|---|---|---|---|---|
| 7-Day Average | 10-Day Average | 14-Day Average | 7-Day Average | 10-Day Average | 14-Day Average | |
| SGRQ Total Score | 0.84 (−2.85, 4.53) | 1.26 (−2.59, 5.11) | 1.87 (−1.96, 5.70) | −0.33 (−4.73, 4.07) | −1.08 (−5.5, 3.3) | −0.87 (−5.41, 3.66) |
| LCQ score | −0.61 (−1.87, 0.65) | −0.80 (−2.13, 0.54) | −0.66 (−2.03, 0.70) | −1.00 (−2.57, 0.57) | −0.97 (−2.55, 0.61) | −0.84 (−2.45, 0.77) |
| KSQ General Health Status | −3.00 (−8.87, 2.88) | −5.3 (−11.35, 0.75) | −6.60 (−12.51, −0.68) * | −1.22 (−8.88, 6.44) | −0.69 (−8.5, 7.1) | −0.48 (−8.37, 7.42) |
| KSQ Lung Health Status | −5.44 (−11.03, 0.15) | −6.93 (−12.67, −1.21) * | −6.91 (−12.73, −1.09) * | −3.57 (−10.9, 3.75) | −2.85 (−10.28, 4.58) | −2.34 (−9.98, 5.19) |
Adjusted association between short-term air pollution exposure (PM2.5 and ozone) and questionnaire outcomes in fibrotic sarcoidosis. Shown are regression coefficients (95% confidence interval) indicating questionnaire score change per IQR increase in air pollution exposure, * = p value < 0.05 for association. Interquartile range (IQR) for PM2.5 averaged over 7, 10, and 14 days = 4.92, 4.64, and 4.38 μg/m3, respectively. IQR for ozone averaged over 7, 10, and 14 days = 0.014, 0.014, and 0.014 ppm, respectively. All models adjusted for age, sex, smoking status, and study drug assignment. SGRQ: St. George’s Respiratory Questionnaire; LCQ: Leicester Cough Questionnaire; KSQ: King’s Sarcoidosis Questionnaire.