Table 1.
Group | Locomotor Activity | Stereotypy Count | Margin Time | Center Time |
---|---|---|---|---|
A | 1626 ± 135 cm | 20.0 ± 2.1 | 157.3 ± 4.1 s | 21.7 ± 4.1 s |
B | 1732 ± 173 cm | 22.2 ± 2.4 | 150.2 ± 3.7 s | 28.8 ± 3.7 s |
AB | 1571 ± 156 cm | 18.3 ± 2.3 | 153.2 ± 4.1 s | 25.8 ± 4.1 s |
C | 1970 ± 198 cm | 15.5 ± 2.2 | 151.3 ± 3.2 s | 27.7 ± 3.2 s |
Behavioral measures (locomotor activity, incidence of stereotypies, performance in an open field test) were obtained as described in detail in Methods. Neither average locomotor activity (F3,20 = 1.12, p = 0.37) nor number of stereotypies (F3,20 = 1.55, p = 0.23) differed between experimental groups. Time spent along the sides (margin time; F3,20 = 0.68, p = 0.57) or in the center of the open field also did not vary across groups (F3,20 = 0.681, p = 0.57). Data are presented as mean ± standard error. A, monoamine oxidase (MAO) A enzyme-inhibited mice (n = 6); B, MAO-B enzyme-inhibited mice (n = 6); AB, MAO-A and MAO-B enzyme-inhibited mice (n = 6); C, control animals (n = 6).