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. 2018 Jun 13;16(6):207. doi: 10.3390/md16060207

Table 1.

List of predicted multi-functional enzymes from the P. variabilis holo-transcriptome with dual catalytic activities.

Unigene ECs Activities Substrate Product
CL12403.Contig1 1.5.1.20 methylenetetrahydrofolate reductase (NAD(P)H) 5-methyltetrahydrofolate 5,10-methylenetetrahydrofolate
2.1.2.1 glycine hydroxymethyltransferase 5,10-methylenetetrahydrofolate tetrahydrofolate
CL12403.Contig2 1.5.1.20 methylenetetrahydrofolate reductase (NAD(P)H) 5-methyltetrahydrofolate 5,10-methylenetetrahydrofolate
2 transferase ? ?
CL2444.Contig1 4.2.1.11 phosphopyruvate hydratase 2-phospho-d-glycerate phosphoenolpyruvate
5.3.1.1 triose-phosphate isomerase d-glyceraldehyde 3-phosphate glycerone phosphate
Unigene12818 1.3.99.1 succinate dehydrogenase succinate fumarate
1.8.4 oxidoreductase, acting on a sulfur group of donors ? ?
5.3.4.1 protein disulfide isomerase -S-S- bonds rearrangement none
Unigene14615 2.4.2.30 NAD ADP-ribosyltransferase NAD+ nicotinamide
2.4.2.31 NAD(P)+protein-arginine ADP-ribosyltransferase NAD+ & protein-l-arginine nicotinamide & protein-omega-N-(ADP-d-ribosyl)-l-arginine
Unigene28009 2.5.1.21 farnesyl-diphosphate farnesyltransferase (2E,6E)-farnesyl diphosphate squalene
1.14 oxidoreductase ? ?
Unigene32504 2.1.1 O-methyltransferase ? ?
2.6.1.42 branched-chain-amino-acid transaminase L-leucine 4-methyl-2-oxopentanoate
Unigene33780 2.7.7.9 UTP:glucose-1-phosphate uridylyltransferase alpha-d-glucose 1-phosphate UDP-glucose
5.3.1.1 triose-phosphate isomerase d-glyceraldehyde 3-phosphate glycerone phosphate
Unigene34807 3.4.21 serine-type endopeptidase ? ?
3.4.24 metalloendopeptidase ? ?
Unigene38918 2.7.2.3 phosphoglycerate kinase 3-phospho-d-glycerate 3-phospho-d-glyceroyl phosphate
4.2.1.11 phosphopyruvate hydratase 2-phospho-d-glycerate phosphoenolpyruvate
Unigene52468 2.1.1 methyltransferase ? ?
2.5.1 transferase, transferring alkyl or aryl groups ? ?
Unigene9562 2.1.2.11 3-methyl-2-oxobutanoate hydroxymethyltransferase 5,10-methylenetetrahydrofolate & 3-methyl-2-oxobutanoate tetrahydrofolate & 2-dehydropantoate
6.3.2.1 pantoate-beta-alanine ligase (R)-pantoate (R)-pantothenate
Unigene9804 2.5.1.21 farnesyl-diphosphate farnesyltransferase (2E,6E)-farnesyl diphosphate squalene
5.3.3.2 isopentenyl-diphosphate delta-isomerase isopentenyl diphosphate dimethylallyl diphosphate