. 2018 Jun 15;5(6):78. doi: 10.3390/children5060078

Table 2.

Clinical management recommendations for children with neuromuscular disease (NMD) on the basis of diagnostic test results.

Recommendation	Diagnostic Test Results
Initiate cough augmentation device	PCF < 270 L/min for children ≥12 years of age
Initiate cough augmentation device	MEP < 60 cmH₂O
Perform overnight sleep monitoring	FVC < 60% predicted
	MIP < 40 cmH₂O
	Clinical symptoms suggestive of SDB
	Loss of ambulation
	Children with NMD that will never have the ability to ambulate
	Infants with NMD
Initiate nocturnal non-invasive ventilation (DMD specifically)	Baseline awake SpO₂ < 95%
	Baseline awake pCO₂ > 45 mmHg
	FVC < 30–50% if undergoing a surgical procedure
	Evidence of SDB on PSG

SDB—sleep-disordered breathing; DMD—Duchenne muscular dystrophy; PSG—polysomnogram