Table 3.
Mean ± SEM number of ovarian follicles in control, PCOS, resveratrol, metformin and metformin+resveratrol treated rats
| Parameters | Control | PCOS | Resveratrol | Metformin | Metformin+Resveratrol | %5 Ethanol | Saline |
|---|---|---|---|---|---|---|---|
| Primordial follicle | 75 ± 2.88 | 20.64 ± 2.68** | 56.56 ± 2.86+ | 56.67 ± 5.01+ | 49.56 ± 4.70+ | 27.86 ± 4.33* | 30.43 ± 4.64* |
| Unilaminar primary follicle | 51.57 ± 6.72 | 33.73 ± 1.63** | 32.78 ± 2.01** | 32.89 ± 0.42** | 32.67 ± 0.53** | 31.71 ± 1.63** | 32.29 ± 5.13** |
| Multilaminar primary follicle | 40.14 ± 0.51 | 21.36 ± 1.50** | 20.78 ± 0.95** | 20.11 ± 0.95** | 20.67 ± 0.78** | 24.57 ± 0.75** | 25.71 ± 1.02** |
| Secondary follicle | 9.29 ± 0.47 | 13.09 ± 0.34** | 9.56 ± 0.44+ | 9.89 ± 0.42+ | 9.56 ± 0.58+ | 12.86 ± 0.4** | 12.86 ± 0.63** |
| Graafian follicle | 7.57 ± 0.65 | 1.73 ± 0.38** | 5.44 ± 0.56+ | 5.11 ± 0.87+ | 6 ± 0.96+ | 2.57 ± 0.97** | 1.86 ± 0.63** |
| Corpus luteum | 13 ± 1.45 | 2 ± 0.36** | 13.22 ± 1.53++ | 13.22 ± 1.38++ | 14.89 ± 1.18++ | 3.57 ± 0.37** | 4.29 ± 0.42** |
| Atretic follicle | 1.43 ± 0.3 | 6.09 ± 0.34** | 1.78 ± 0.32++ | 2.67 ± 0.33++ | 2.56 ± 0.44++ | 5.43 ± 0.65** | 5.14 ± 0.34** |
Values are expressed as mean ± SEM
*, ** versus control group; P < 0,05 and P < 0.001, respectively
+, ++ versus PCOS group; P < 0,05 and P < 0.001, respectively