Table 1.
The mRNA expressions of glucose metabolic markers in three EMT types of CTCs (Cohort 1a)
| Target probe | Positive/ total CTCs | Positive/Negative in 3 types | χ2 | P | ||
|---|---|---|---|---|---|---|
| E-CTCs | H-CTCs | M-CTCs | ||||
| HK2 | 4/25 (0.16) | 0/9 | 4/4 | 0/8 | 7.595 | 0.011* |
| PDP2 | 30/39 (0.77) | 4/2 | 21/2 | 5/5 | 7.045 | 0.030* |
| G6PD | 37/50 (0.74) | 2/0 | 25/1 | 10/12 | 16.41 | 0.001* |
| PGK1 | 25/61 (0.41) | 1/6 | 15/26 | 9/4 | 6.929 | 0.031* |
| PHKA1 | 28/42 (0.67) | 7/4 | 17/2 | 4/8 | 10.98 | 0.004* |
| PYGL | 44/59 (0.75) | 5/5 | 27/8 | 12/2 | 3.925 | 0.141 |
| PDK1 | 45/70 (0.64) | 5/9 | 23/11 | 17/5 | 6.761 | 0.034* |
| PKM2 | 68/90 (0.76) | 16/2 | 36/4 | 16/16 | 17.18 | 0.001* |
*P < 0.05
aCohort 1 includes 64 patients pathologically diagnosed with common cancer