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. 2018 Jun 13;12(6):e0006575. doi: 10.1371/journal.pntd.0006575

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© 2018 Chadha et al

This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

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Fig 7 — (A) and (B) Inhibition profile of borrelidin for the promastigote (A) and intracellular amastigote (B) growth of WT parasites. Percentage parasite survival was plotted against different concentrations of borrelidin. (C) and (D) The leishmanicidal effect of borrelidin was checked on promastigotes (C) and amastigotes (D) of WT, ThrRS/NEO and ThrRS/NEO[pThrRS⁺] parasites. The mean IC₅₀ values were calculated for borrelidin and plotted as bar graphs. (E) The effect of miltefosine on WT, ThrRS/NEO and ThrRS/NEO[pThrRS⁺] promastigotes. The bar graphs represent mean ± SD with n = 3. * p < 0.05.