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IC50 Concentration of Inhibitors
| Inhibitor | Cell Lines | ||
|---|---|---|---|
|
| |||
| MCF-7aro | LET-R | RAD-R | |
| Erlotinib (EGFR) | 1036nM | 9375nM | 2651nM |
| Everolimus (mTORC1) | 250nM | 2000nM | 8000nM |
| Lapatinib (HER2) | 1698nM | 2148nM | 389nM |
| MK-2206 (AKT) | 90nM | 80nM | 22nM |
| MLN0128 (mTORC1/2) | 5nM | 10nM | 50nM |
| Palbociclib (CDK4/6) | 50nM | 5000nM | 10000nM |
| PPP (IGF1R) | 69nM | 103nM | 84nM |
