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. Author manuscript; available in PMC: 2019 Jul 17.
Published in final edited form as: AIDS. 2018 Jul 17;32(11):1465–1474. doi: 10.1097/QAD.0000000000001854

Figure 1. Epigenetic age acceleration versus HIV status.

Figure 1

A,B) The x axis reports 3 groups: HIV negative controls, HIV+ adolescents with non-detectable viral load (orange bar), and HIV+ individuals with detectable viral load (red bar). A) The y-axis reports the mean age acceleration residual based on Horvath 2013. B) Extrinsic epigenetic age acceleration (y-axis). The title of the bar plots reports the Kruskal Wallis p value.

C,D) ARV treatment failure (x-axis) versus C) AgeAccelerationResidual and D) EEAA. The group with ARV.line=3 corresponds to HIV+ adolescents who failed the ARV treatment repeatedly.

E,F) Observed CD4+ T cell count versus epigenetic age acceleration in HIV+ adolescents. Points are colored by HIV viral load status (red=detectable virus).