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. Author manuscript; available in PMC: 2019 Jul 1.
Published in final edited form as: Heart Rhythm. 2018 Feb 16;15(7):1072–1080. doi: 10.1016/j.hrthm.2018.02.018

Figure 6. HuR increased sodium currents.

Figure 6

(A) Plasmids (pEGFP-C1-SCN5A-ORF-3′ARE2) were transfected into HEK293 cells with TetOn-HuR. Forty-eight hours after transfection, sodium currents were measured by patch clamp. Sodium currents are shown as the mean peak current ± SE. (*P<0.05). (B) Sodium currents were measured in primary cardiomyocytes isolated from mice treated with either AAV-control (n=14) or AAV-HuR (n=25). The peak current densities of Na+ currents at −30 mV are shown as mean + SE (*P<0.05).