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. 2018 Jun 29;8:9821. doi: 10.1038/s41598-018-28183-6

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© The Author(s) 2018

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Increased IL-1β levels in aqueous humor. (A) The concentration level of IL-1β was measured in rat serum at 3, 7, and 14 days after immunization. The levels of IL-1β were comparable in both groups at all points in time. (B) IL-1β was also analyzed in aqueous humor 3, 7, and 14 days after immunization. While no changes were noted at 3 days (p > 0.05), a significant increase of IL-1β could be observed in the S100 group after 7 days (p = 0.03). At 14 days, the IL-1β concentration level was comparable in both groups. Values are mean ± SEM.