Figure 1.

Melanin production of individual C. neoformans var. neoformans strains in different environmental conditions. The melanin production of 54 C. neoformans var. neoformans strains was quantified in 8 different conditions: from left, 30 °C, 37 °C, low (0.25 mM H₂O₂), intermediate (0.5 mM H₂O₂) and high (1 mM H₂O₂) oxidative stress, and low (0.25 mM NaNO₂), intermediate (0.5 mM NaNO₂) and high (1 mM NaNO₂) nitrosative stress. Pigment density of the colonies was measured following 3-days’ growth on caffeic acid agar medium. Colonies of a few representative strains from 30 °C are shown on left.