Table 1.
Strains of C. neoformans var. neoformans (serotype D) analyzed in this study.
| Strain code | Category | Origin | Source | Year isolated | Underlying condition | Molecular Type | Mating type |
|---|---|---|---|---|---|---|---|
| B3176 | ENV | Denmark | Pigeon nest | 1970 | α | ||
| B3179 | CLN | Maryland, USA | CSF | α | |||
| CAP67-2 | CLN | USA | α | ||||
| GRACA18BK1–3 | ENV | Greece | Eucalyptus tree | 2013 | — | VNIV | a |
| GRACP15SO1–2 | ENV | Greece | Pine tree | 2013 | — | VNIV | a |
| GRACP30BK1–1 | ENV | Greece | Plane tree | 2013 | VNIV | a | |
| GRAKI13HO1–1 | ENV | Greece | Plane tree | 2013 | VNIV | a | |
| GRAKI28HO1–1 | ENV | Greece | Olive tree | 2013 | VNIV | a | |
| GRLMM26HO1–2 | ENV | Greece | Olive tree | 2013 | — | VNIV | a |
| ITMPV22BK7–1 | ENV | Italy | Oak tree | 2014 | — | VNIV | α |
| IUM 01-0956 | SCC | Italy | Skin, head | 2001 | AIDS | VNIV | α |
| IUM 01-4729 | ENV | Belgium | Pigeon droppings | 2001 | — | VNIV | α |
| IUM 01-4730 | ENV | Belgium | Dust | 2001 | — | VNIV | α |
| IUM 02-0826 | VET | Italy | Cat | 2002 | — | VNIV | a |
| IUM 02-4295 | PPCC | Italy | Skin | 2002 | No known risk factors | VNIV | a |
| IUM 77-0033 | SCC | Italy | Skin, right ear | 1977 | No known risk factors | VNIV | α |
| IUM 79-0801 | PCC | Italy | Skin, left leg | 1979 | Common variable immunodeficiency | VNIV | α |
| IUM 93-1656 | DC | Italy | CSF | 1993 | AIDS | VNIV | α |
| IUM 97-4899 | PPCC | Belgium | Skin | 1997 | No risk factors | VNIV | α |
| IUM 98-2742 | SCC | Italy | Skin, left hand | 1998 | AIDS | VNIV | α |
| IUM 98-4987 | PPCC | Italy | Skin | 1998 | Breast tumor | VNIV | α |
| IUM 98-5036 | CLN | Belgium | Skin | 1998 | Diabetes | VNIV | α |
| JEC20 | LAB | VNIV | a | ||||
| JEC21 | LAB | VNIV | α | ||||
| M9112 | PCC | Japan | Skin | 1985 | No known risk factors | VNIV | α |
| MAS92-0088 | CLN | USA | Blood | VNIV | α | ||
| MAS92-0111 | CLN | USA | VNIV | α | |||
| MAS92-0226 | CLN | USA | VNIV | α | |||
| MAS92-0232 | CLN | USA | VNIV | α | |||
| MAS92-0397 | CLN | USA | VNIV | α | |||
| MAS92-0403 | CLN | USA | VNIV | α | |||
| MAS92-0621 | CLN | USA | VNIV | α | |||
| MAS92-0764 | CLN | USA | VNIV | α | |||
| MAS93-0216 | CLN | USA | VNIV | α | |||
| MAS94-0176 | CLN | USA | VNIV | α | |||
| NIH-116 | ENV | Virginia, USA | Pigeon nest | 1960 | — | VNIV | α |
| NIH-424 | ENV | Denmark | Pigeon nest | 1970 | — | VNIV | α |
| NIH-426 | ENV | Denmark | Pigeon nest | 1970 | — | VNIV | α |
| NIH-430 | ENV | Denmark | Pigeon nest | 1970 | — | VNIV | a |
| NIH-431 | ENV | Denmark | Pigeon nest | 1970 | — | VNIV | α |
| NIH-432 | ENV | Denmark | Pigeon nest | 1970 | — | VNIV | α |
| NIH-433 | ENV | Denmark | Pigeon nest | 1970 | — | VNIV | a |
| NIH-434 | ENV | Denmark | Pigeon nest | 1970 | — | VNIV | α |
| NIH-442 | ENV | Denmark | Pigeon nest | 1970 | — | VNIV | α |
| PD1596 | VET | Italy | Cat | 2010 | — | VNIV | α |
| PD32 | VET | Italy | Cat | 2009 | — | VNIV | α |
| RKI 13-0490 | ENV | Germany | Pigeon droppings | 2013 | — | VNIV | a |
| RKI 13-0491 | ENV | Germany | Pigeon droppings | 2013 | — | VNIV | a |
| RKI 13-0492 | ENV | Germany | Pigeon droppings | 2013 | — | VNIV | a |
| RKI 14-1061.4 | ENV | Germany | a | ||||
| TRNCGB1H01-1 | ENV | Turkey | Pine tree | 2013 | — | VNIV | α |
| Y286-90 | CLN | Canada | CSF | VNIV | α | ||
| Y290-90 | CLN | Canada | CSF | VNIV | α | ||
| Y494-91 | CLN | Atlanta, USA | VNIV | α |
PCC = primary cutaneous cyrptococcosis; PPCC = probable primary cutaneous cryptococcosis; SCC = secondary cutaneous cryptococcosis; DC = disseminated cryptococcosis; ENV = environment; VET = veterinary; CLN = clinical; CSF = cerebrospinal fluid; LAB = laboratory.