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. 2018 Jun 29;8:9875. doi: 10.1038/s41598-018-28072-y

Table 2.

Data after the index ablation and from the 3-month electrophysiology procedure.

Total
(n = 41)
ERAF
(n = 17)
No ERAF
(n = 24)
Univariate p
AADs at discharge after the index CA
Propafenone 21 (51.2%) 9 (52.9%) 12 (50.0%) 0.853
Amiodarone 8 (19.5%) 4 (23.5%) 4 (16.7%) 0.586
Sotalol 8 (19.5%) 3 (17.6%) 5 (20.8%) 0.800
Beta-blockers 3 (7.3%) 0 (0%) 3 (12.5%) 0.999
Verapamil 1 (2.4%) 1 (5.9%) 0 (0%) >0.999
Inflammatory markers after the index CA
Leukocytes (n, 109/l) 9.0
(7.4–10.7)
8.0
(6.9–10.8)
9.0
(8.0–10.5)
0.843
Neutrophiles (n, 109/l) 6.0 (5.0–8.0) 6.0 (4.9–7.8) 6.0 (5.3–8.5) 0.886
ESR (mm/h) 12.0
(8.0–22.0)
10.0
(6.0–16.0)
13.0
(10.0–26.0)
0.074
Fibrinogen (g/l) 3.5 ± 0.9 3.3 ± 1.0 3.7 ± 0.9 0.249
CRP (mg/l) 12.1
(7.4–19.0)
12.6
(8.0–22.0)
11.5
(6.6–16.0)
0.222
Troponin I (ng/l) 6.0 (5.0–9.0) 5.0 (3.6–9.5) 6.5 (6.0–9.0) 0.719
CK-MB (u/l) 19.0
(16.5–23.5)
19.0
(15.0–22.0)
21.0
(18.0–25.0)
0.287
3-month Follow-up EP procedure
PV reconnection 25 (61.0%) 15 (88.2%) 10 (41.7%) 0.006
Left PVs reconnection 15 (36.6%) 8 (47.1%) 7 (29.2%) 0.245
Right PVs reconnection 21 (51.2%) 14 (82.4%) 7 (29.2%) 0.002
PVs with late reconnection (n) 1.0 (0.0–2.0) 2.0 (1.0–4.0) 0.0 (0.0–2.0) 0.007
Left PVI segments with reconnection (n) 0.0 (0.0–1.0) 0.0 (0.0–1.0) 0.0 (0.0–1.0) 0.170
Right PVI segments with reconnection (n) 1.0 (0.0–1.0) 1.0 (1.0–2.0) 0.0 (0.0–1.0) 0.002
Gap in the Roof line 13 (31.7%) 9 (52.9%) 4 (16.7%) 0.018
Gap in the Mitral isthmus line 15 (36.6%) 6 (35.3%) 9 (37.5%) 0.885

Data are presented as mean ± standard deviation, median (25th to 75th percentile) or numbers (percentages).

ERAF, early recurrence of atrial fibrillation; AAD, anti-arrhythmic drug; CA, catheter-ablation; ESR, erythrocyte sedimentation rate; CRP, C-reactive protein; CK-MB, creatin-kinase MB iso-enzyme; EP, electrophysiology; PV, pulmonary vein; PVI, pulmonary vein isolation.