A, B, Serum CA-125 levels are associated with (A) menopausal status (P < .001) and (B) pleural effusions (P < .001). Each diamond or square represents the level of serum CA-125 at a visit. A, Blue squares are levels in postmenopausal patients, and red diamonds are levels in premenopausal patients. B, Blue squares are levels in patients with pleural effusions, and red diamonds are levels in patients without pleural effusions. The arrowhead and line mark the threshold level of 34 U/mL. See Figure 1 legend for expansion of abbreviation.