Table 1.
Characteristics of Patients Providing Samples for Full Data Set and Selected Samples for Microarray Analysis
| Characteristic | Full Sample Set (n = 15) | Samples in Microarray Study (n = 6) |
|---|---|---|
| Age, y | 50.9 ± 10.7 | 52.3 ± 9.1 |
| Sex | 6 male/9 female | 1 male/5 female |
| AHI, events/h TST | ||
| Pretreatment (PRE group) | 85.0 ± 30.9 | 91 ± 28.5 |
| Post-treatment (POST group) | 11.3 ± 11.4 | 3.8 ± 3.3 |
| Difference (PRE − POST) | 73.6 ± 31.2 | 87.3 ± 28.2 |
| 4% ODI, events/h TST | ||
| Pretreatment (PRE group) | 95.73 ± 35.13 | 108.22 ± 34.36 |
| Post-treatment (POST group) | 12.37 ± 13.99 | 4.43 ± 4.17 |
| Difference (PRE − POST) | 83.35 ± 36.39 | 103.78 ± 33.90 |
| T90, min | ||
| Pretreatment (PRE group) | 220.61 ± 95.40 | 221.60 ± 82.72 |
| Post-treatment (POST group) | 32.11 ± 37.70 | 7.17 ± 9.59 |
| Difference (PRE − POST) | 188.51 ± 104.28 | 214.43 ± 87.76 |
| Spo2 nadir, % | ||
| Pretreatment (PRE group) | 56.90 ± 8.12 | 57.78 ± 4.96 |
| Post-treatment (POST group) | 78.81 ± 10.91 | 83.45 ± 10.45 |
| Difference (PRE − POST) | 21.91 ± 10.82 | 25.67 ± 8.93 |
| Paco2, mm Hg | ||
| Pretreatment (PRE group) | 50.91 ± 7.11 | 48.35 ± 2.48 |
| Post-treatment (POST group) | 42.82 ± 6.58 | 41.03 ± 4.74 |
| Difference (PRE − POST) | 8.09 ± 4.63 | 7.32 ± 3.20 |
| BMI, kg/m2 | ||
| Pretreatment (PRE group) | 49.38 ± 10.23 | 50.70 ± 14.33 |
| Post-treatment (POST group) | 48.36 ± 8.31 | 48.97 ± 10.57 |
| Difference (PRE − POST) | 1.02 ± 2.85 | 1.73 ± 4.50 |
| Smoking status | 3 crt, 3 pst, 9 nvr | 1 crt, 1 pst, 4 nvr |
| Hypertension | 13/15 patients (86.7%) | 4/6 patients (66.7%) |
| Type 2 diabetes mellitus | 5/15 patients (33.3%) | 1/6 patients (16.7%) |
| Congestive heart failure | 6/15 patients (40.0%) | 1/6 patients (16.7%) |
| Dyslipidemia | 4/15 patients (26.7%) | 1/6 patients (16.7%) |
Data are shown as means ± SD. crt = current smoker; nvr = never smoker; ODI = oxygen desaturation index; POST group = patients from whom blood was collected 6 weeks after positive airway pressure treatment; PRE group = patients from whom blood was collected before starting positive airway pressure treatment; pst = past smoker; Spo2 = oxygen saturation as determined by pulse oximetry; T90 = time spent at less than 90% oxygen saturation.