Table 1.
Demographics and Clinical Characteristics of Patients With Bronchiectasisa
| Characteristic | Data Available (No.) | Overall (N = 1,826) | NTM (n = 1,158) | No NTM (n = 668) | P Valueb |
|---|---|---|---|---|---|
| Sex, No. (%) | 1,826 | ||||
| Female | 1,439 (79) | 964 (83) | 475 (71) | < .01 | |
| Age, mean ± SD, y | 1,823 | 64 ± 14 | 66 ± 12 | 61 ± 17 | < .01 |
| Age at diagnosis, mean ± SD, y | 1,456 | 57 ± 17 | 59 ± 15 | 53 ± 19 | < .01 |
| Race/ethnicity, No. (%) | 1,709 | ||||
| Non-Hispanic white | 1,514 (89) | 1,003 (91) | 511 (85) | < .01 | |
| Non-Hispanic black | 34 (2) | 7 (1) | 27 (4) | ||
| Hispanic | 73 (4) | 41 (4) | 32 (5) | ||
| Asian | 60 (4) | 41 (4) | 19 (3) | ||
| Other | 28 (2) | 16 (1) | 12 (2) | ||
| Primary insurance, No. (%) | 1,684 | ||||
| Commercial | 794 (47) | 504 (48) | 290 (46) | < .01 | |
| Medicaid and other state programs | 49 (3) | 24 (2) | 25 (4) | ||
| Medicare | 749 (44) | 485 (46) | 264 (42) | ||
| No insurance | 18 (1) | 9 (1) | 9 (1) | ||
| Other (including Tricare) | 74 (4) | 29 (3) | 45 (7) | ||
| BMI, mean ± SD, kg/m2 | 1,812 | 23.2 ± 5.7 | 22.5 ± 5.5 | 24.3 ± 5.8 | < .01 |
| q1, q3, | 19.9, 25.1 | 19.7, 24.3 | 20.3, 26.8 | ||
| Smoking, No. (%) | 1,815 | ||||
| Never | 1,094 (60) | 686 (60) | 408 (61) | .74 | |
| Former | 693 (38) | 447 (39) | 246 (37) | ||
| Current | 28 (2) | 18 (2) | 10 (2) | ||
| Chest wall deformity, No. (%) | 1,731 | ||||
| None | 1,657 (96) | 1,038 (96) | 619 (96) | .02 | |
| Pectus excavatum | 56 (3) | 39 (4) | 17 (3) | ||
| Other | 18 (1) | 6 (1) | 12 (2) | ||
| Otitis or rhinosinusitis, No. (%) | 1,562 | ||||
| Yes | 388 (25) | 222 (23) | 166 (29) | < .01 | |
| Comorbidities, No. (%) | |||||
| History of pneumonia | 1,745 | 1,187 (68) | 758 (69) | 429 (67) | .45 |
| COPD | 1,778 | 350 (20) | 217 (19) | 133 (20) | .60 |
| Asthma | 1,783 | 515 (29) | 298 (26) | 217 (33) | < .01 |
| GERD | 1,789 | 841 (47) | 577 (51) | 264 (40) | < .01 |
| Rheumatologic disease | 1,775 | 142 (8) | 87 (8) | 55 (8) | .60 |
| Chronic ulcerative colitis or Crohn’s disease | 1,795 | 47 (3) | 26 (2) | 21 (3) | .25 |
| Primary immunodeficiency | 1,776 | 89 (5) | 44 (4) | 45 (7) | < .01 |
| Primary ciliary dyskinesia | 1,791 | 52 (3) | 20 (2) | 32 (5) | < .01 |
| Prior tuberculosis, No. (%) | 1,781 | ||||
| Yes | 70 (4) | 50 (4) | 20 (3) | .14 | |
| History of pulmonary exacerbation in the past 2 y, No. (%) | 1,754 | 1,124 (64) | 687 (62) | 437 (68) | .01 |
| No. of pulmonary exacerbations in the past 2 y, No. (%) | 992 | 3.0 ± 2.8 | 2.7 ± 2.3 | 3.4 ± 3.3 | < .01 |
GERD = gastroesophageal reflux disease; NTM = nontuberculous mycobacteria.
Percentages and other descriptive statistics calculated after excluding participants with missing data from the column total. Less than 1% of participants had missing data for all items except the following: age at diagnosis (30%), race/ethnicity (6%), primary insurance (8%), chest wall deformity (5%), history of pneumonia (4%), otitis or rhinosinusitis (14%), respiratory distress at birth (17%), COPD (3%), asthma (2%), GERD (2%), rheumatologic disease (3%), chronic ulcerative colitis or Crohn’s disease (2%), primary immunodeficiency (3%), primary ciliary dyskinesia (2%), and prior tuberculosis (2%).
P values for categorical variables are from χ2 tests, and from t tests for continuous variables comparing patients with NTM vs patients without NTM.